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Several research findings suggest that oxidative damage resulting from disproportion between reactive oxygen metabolites (ROMs) production and antioxidant activity generates deleterious effects on signal transduction, mitochondrial complex (I-IV) activities, structural plasticity, oxidation of proteins, and lipid peroxidation in membranes and genes leading to neuronal death (Takuma et al., 2004)
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Y lo que sí es nuevo –como el uso de biomarcadores sin validación clínica y el uso imprudente de péptidos no regulados– carece, en el mejor de los casos, de evidencia suficiente sobre sus beneficios, y en el peor, podría ser perjudicial