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Enzymes involved in both processes including carbamoyl phosphate synthetase-1 ( Cps1 ), argininosuccinate synthetase 1 ( Ass1 ), argininosuccinate lyase ( Asl ), ornithine-aminotransferase ( Oat ), and proline dehydrogenase ( Prodh ) are up-regulated in fasting (Sokolović et al

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This is the strict liability principle under the WADA Code