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Secondary endpoints included the proportion of participants achieving ≥5% and ≥10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and β-cell function

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Therefore, if epitalon binds to and inhibits H1.3 in the cancer cells, H19 would be derepressed

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