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Gene expression of sod were increased 3.9, 5.2, and 5.9-fold in multi-copy recombinants S-3/pKLH337, S-3/pKLH341, and S-3/pKLH344 compared to one copy S-3/pKLH167
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No significant differences were observed in the incidence rate of adverse events when comparing males and females: all-cause mortality (12.5 vs 8.79, p=0.62), liver-related events (48.4 vs 49.6, p=0.96), decompensated cirrhosis (37.4 vs 32.8, p=0.54), HCC (3.5 vs 11.1, p=0.37), fibrosis progression (48.9 vs 52.1, p=0.87), CVD (30.8 vs 30.8, p=0.99), type 2 diabetes (23.5 vs 22.3, p=0.81), and non-liver cancer (10.7 vs