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These studies in yeast provided the first direct evidence for ATP-dependent, low-affinity transport of GSH in any cell type (Rebbeor et al., 1998a), and demonstrated that this ATP-dependent GSH transport in yeast is mediated by Ycf1p, the yeast orthologue of mammalian MRP1 and MRP2 (Rebbeor et al., 1998b)

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Semaglutide Dosing# Semaglutide for weight management (Wegovy) requires a 16-week dose escalation from 0.25 mg to the target 2.4 mg weekly dose (0.25, 0.5, 1.0, 1.7, 2.4 mg at 4-week intervals)