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Lipidation of peptides via chemical modification with fatty acids can represent a necessary approach to increase lymphatic transport by improving interactions with chylomicrons, and it has been applied in the oral delivery of several peptides [77]

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IL-35 levels are lower in untreated patients with MG, particularly those with GMG or comorbid thymoma (116), but they increase following treatment and are negatively associated with functional disability scores (123), highlighting the importance of IL-35 in MG disease outcomes