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For the induction of an oxidative stress response, βOHB may bypass the hormesis route and directly promote the gene expression of the anti-oxidant protein metallothionein and of the transcription regulator FOXO3a which mediates many protective actions of sirtuins

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In addition, male rats subjected to a disrupted daily rhythm and administered normal amounts of VB6 and vitamin B 1 , along with high amounts of pantothenic acid, experienced a reduction in the suppression of gonadal development [26]