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Some scholars have proposed autoimmune mechanisms, chronic liver diseases, schistosomiasis, and malnutrition as potential cirrhosis causes, yet these remain contentious and necessitate further investigation ( Liver cirrhosis represents a post-injury liver repair response wherein hepatic stellate cell (HSC) activation plays a pivotal role, alongside liver sinusoidal endothelial cells (LSECs) regulation, cytokine release, and fibrous scar tissue deposition (Kisseleva and Brenner, 2021)

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In general, liposomes used in medical applications range from 50 to 450 nm [215] (Table 1)