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Quercetin prevented VPA-induced behavioral impairments and attenuated oxidative alterations across multiple brain regions, supporting its antioxidant and neuroprotective potential in this ASD model ( Since quercetin itself in low concentrations is poorly absorbed, can hardly cross the BBB and is quickly eliminated, the study of Moghaddam used quercetin-loaded nanophytosome (QNP) against autism-like damage in maternal separation model

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Usage Period:90 days

2006 Nov;12(9):857-62