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From a mechanistic point of view, these diseases involve a de-regulation of several overlapping and interacting signaling pathways, and recent in vitro and in vivo studies revealed that the main targets of lactoferrin action in this context are represented by PPARγ and TLR4-NF-κB pathways, both representing key players in inflammatory responses and immune homeostasis maintenance [153,154]

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Case Report A 73-year old lady presented to our emergency department following a sudden onset of central, non-radiating chest heaviness 8 hours prior