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Even with recompression therapy, DCS SCI frequently results in permanent neurological deficits and long-term disability ( Bubble formation during decompression is the primary cause of DCS SCI ( Hyperbaric oxygen (HBO) therapy, defined as breathing 100% O 2 under increased atmospheric pressure, is widely used in DCS treatment ( In this study, primary rat spinal astrocytes were used to establish a bubble contact model that mimics the mechanical damage induced by DCS SCI

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