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Finally, we also review the therapeutic efficacy of mTORC1 inhibitors in cancer treatments, considering its use in combination with other drugs, with particular focus on cellular metabolism inhibitors, that could help improve their anti neoplastic effect and eliminate cancer cells in patients

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Studies have demonstrated that elevated nitrogen supply, particularly from ammonium sources, significantly increases protein accumulation in purslane leaves, while excessive nitrogen beyond an optimal threshold reduces water-soluble proteins in shoots suggesting a non-linear relationship between nitrogen availability and protein yield (Szalai et al., 2010