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Model‐Informed Assessment of Probability of Phase 3 Success for Ritlecitinib in Patients with Moderate‐to‐Severe Ulcerative Colitis - Wojciechowski - 2024 - Clinical Pharmacology & Therapeutics - Wiley Online Library

“nasa_rs”: “JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age“

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They are a reasonable low-risk experiment for mild loss but not a reliable replacement for proven treatment