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For example, NAPQI, the toxic metabolite, is primarily the product of CYP2E1 metabolism, and there is evidence that younger children have a relative immaturity in CYP2E1 metabolism, which would substantially reduce the production of this toxic metabolite in infants

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Assessment of CYP2C9, CYP2C19, and CYP2D6 polymorphisms in allergic patients with chemical sensitivity

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