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Psychiatry 80, 291–294

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SLC25A45 drives carnitine biosynthesis in BBOX1 -expressing cells We reasoned that AsPC-1 cells are unable to produce carnitine de novo (Figures 3C and 3G) because they lack the alpha-ketoglutarate-dependent gamma-butyrobetaine dioxygenase 1 (BBOX1) (Figure 3A)