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Unlike rd10 , which carries a missense mutation in exon 13 of phosphodiesterase 6B ( Pde6b ) 29 , the Rho P23H model carries the p.Pro23His mutation in the rhodopsin gene and shows progressive retinal degeneration similar to that seen in patients with autosomal dominant retinitis pigmentosa 32

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For TPCA analysis of the IB-DNQ and Rucaparib studies in TNBC cells, we employed the Rtpca R-package which uses annotated protein interaction databases (CORUM and BioGRID were used here) and measures Euclidean distance between protein melt curves to identify protein-protein interaction changes (86)

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