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Similarly, research carried out to determine the efficiency of a new fluorophore, Pl-Cys, a unique ESIPT dye connected to an acrylate group through a hydroxyl moiety, revealed that in the presence of Cys, the acrylate moiety splits off from Pl-Cys and Cys and, in turn, interacts with Pl-Cys, triggering the ESIPT phenomenon

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Reduced form of glutathione is required for many critical cellular processes and plays a cardinal role in cell maintenance and regulation of the thiol-redox [37]