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ACL-derived fibroblasts had significantly larger total enzymatic crosslinking content (total divalent crosslinks plus pyridinoline crosslinks) and increased PLOD1/2 , LOX , Col1a1 , and Col3a1 expression, compared to MCL-and patellar-tendon-derived fibroblasts, with no differences between MCL and patellar tendon cells (Kato et al ., 2015)