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Activation of TLR3 by poly(I:C) synergistically worsened arthritis in rats, while its blockade resulted in a reduction of inflammatory manifestations

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The Clairafly™ trial focuses on evaluating BI 1291583s safety, tolerability, pharmacodynamics, and pharmacokinetics in adult patients with cystic fibrosis-related bronchiectasis (National Library of Medicine, 2024)