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[DOI] [PMC free article] [PubMed] [Google Scholar] Tiedge M, Lortz S, Drinkgern J, Lenzen S

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Ligand binding to TLRs typically recruits the adaptor protein myeloid differentiation primary response 88 (MyD88), thereby triggering major pro-inflammatory signaling cascades, including the MAPK and nuclear factor kappa B (NF-κB) pathways (165, 259)