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154 Function in neurodegenerative diseases Alzheimer’s disease Alzheimer’s disease (AD) affects ~50 million people worldwide and is characterized by cognitive impairment that is associated with a progressive decline in memory, impaired self-care, disorientation, and personality changes

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3 Functional roles and mechanistic basis of nanoencapsulation in nutraceuticals In the preceding section, we examined the technological evolution of nanoencapsulation in nutraceuticals, tracing its trajectory from conceptual foundations and early prototypes- such as liposomes and solid lipid nanoparticles- to contemporary multifunctional and stimuli-responsive delivery platforms