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As MASLD and hypertension are common co-morbidities, a study regarding differences in GSTM1 and GSTO1 protein expression in normotensive and hypertensive rats was performed which showed significant GSTO1 downregulation and no change in GSTM1 levels in hypertensive rats (Svoboda and Kawaja 2012)

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Think of it like this – your muscles have an internal GPS that keeps them from going too far in any direction