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Although further studies are warranted, dual β-lactam therapy, including combinations with avibactam, is promising, especially for those who may not tolerate amikacin or tigecycline

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Previous studies have reported a noticeable increase in the expression of GSH synthesis enzymes (GCLM, GCLC, and GS) and l-cysteine transporters (ASCT1/2, solute carrier family 3 member 2 [SLC3A2], and SLC7A11) in various types of cancers (12–14)