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Several concerns have been raised demonstrating phthalates effect on granulosa cell steroidogenesis in humans (118), mice (108), and rats (119), and increase cell proliferation in swine when exposed to NPs with their composite EDCs (120)

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We first provide an overview of the critical functions of DNA methylation and demethylation in retinal development and cellular differentiation, followed by an in-depth discussion of their diverse roles in retinal diseases