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[DOI] [PubMed] [Google Scholar] 174.Drmic D., Samara M., Vidovic T., Malekinusic D., Antunovic M., Vrdoljak B., Ruzman J., Milkovic Perisa M., Horvat Pavlov K., Jeyakumar J., et al

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One of MOTS-C's downstream effects is increasing intracellular NAD+ utilization — the mitochondria are running harder, so they're consuming more of the NAD+ pool