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Respiratory Acid-Base Disorders Respiratory acidosis (pH 7.45, decreased): Caused by excessive removal through hyperventilation Common causes: anxiety/panic attacks, pain, fever, high altitude Symptoms: dizziness, lightheadedness, numbness and tingling in extremities (paresthesia) Compensation: kidneys excrete more Metabolic Acid-Base Disorders Metabolic acidosis (pH 7.45, elevated): Caused by acid loss or bicarbonate accumulation Common causes: prolonged vomiting (loss of from the stomach), excessive diuretic use, hypokalemia Symptoms: muscle twitching, irritability, cardiac arrhythmias in severe cases Compensation: hypoventilation to retain (though this compensation is limited because the body won't suppress breathing enough to cause dangerous hypoxia) Treatment of Acid-Base Disorders Treatment always targets the underlying cause first: Respiratory acidosis : Improve ventilation (bronchodilators, mechanical ventilation if needed), treat the underlying lung or neurological condition
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There are multiple issues (e.g., economic, technological, and ethical) that need to be addressed if such a paradigm is to be adopted (Chap