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Within the last years, it became evident that renal tubular ferroptosis, a modality of regulated necrosis caused by iron-dependent lipid peroxidation [3], is a pathophysiological hallmark of IRI, raising considerable interest in the development of preventive strategies upon solid organ transplantation [4]

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โ€œGTP Cyclohydrolase I Expression, Protein, and Activity Determine Intracellular Tetrahydrobiopterin Levels, Independent of GTP Cyclohydrolase Feedback Regulatory Protein Expression.โ€ The Journal of Biological Chemistry , vol

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