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The framework offers insights into potential therapeutic targets, such as strengthening gut barrier integrity or modulating cytokine-HPA axis coupling, to restore robust information flow and shift the system away from pathological operating points.

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The simplest way to think about it: Wegovy® and Zepbound® work by targeting specific receptors in your body—Wegovy® focuses on GLP-1, while Zepbound® activates both GLP-1 and GIP receptors