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The latter option, that loss of oxidants can augment apoptosis, is supported by findings that correlate increased cellular hydrogen peroxide levels with resistance to apoptotic signaling in some cell systems (18, 86), as catalase overexpression in either cytoplasmic or mitochondrial compartments potentiated apoptosis, whereas inhibiting endogenous catalase promoted cell survival

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Nicotinamide Adenine Dinucleotide (NAD+) is a naturally occurring coenzyme found in every cell of the body and plays a critical role in converting nutrients into energy while supporting DNA repair and overall cellular function