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Despite advances in treatment modalities, such as targeted therapy and immunotherapy, the development of pharmacological resistance poses a critical challenge, undermining treatment efficacy and leading to disease recurrence and metastasis

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Feature Injection Oral Supplement Absorption Rate Near 100% Variable (30–70%) Works with gut issues ✔ Yes ✘ No Speed of level increase Days to weeks Weeks to months Daily pill burden ✔ None ✘ Daily Clinically supervised dose ✔ Yes ✘ Self-managed Suitable for severe deficiency ✔ Preferred Often insufficient