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In 2012, Dixon and team initially pinpointed Fer-1 emerged as the most potent blocker of Erastin-evoked ferroptosis in HT-1080 fibrosarcoma cells ( Fer-1 quelled angiotensin-II-provoked inflammatory cascades and stellate-cell ferroptosis by dampening ROS surge and repressing Nrf2 together with GPX expression (Li et al., 2019

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