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As with HPA axis activation influencing sleep, complex regulatory action of sleep upon HPA axis function influences stress responses

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(These interventions are discussed further in the Nutritional Status and Cachexia section of this protocol.) A rigorous study found that all tyoes of exercise (not just aerobic exercise) improved quality of life and fatigue in individuals undergoing cancer treatment, particularly when the exercise was moderate to vigorous in intensity (Mishra 2012)