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The relevance of this incomplete list is to highlight that irreversible inactivation, rather than reversible regulation, can occur through the reaction of the same redox-activated control motifs (cystine thiol(ate) residues) with EdAG, rather than with the physiologically appropriate actuator (glutathione sulphinate, glutathione disulphide)

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Dimitris Kounatidis, Email: [email protected]