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[DOI] [PubMed] [Google Scholar] 105.Cuartero M.I., García-Culebras A., Nieto-Vaquero C., Fraga E., Torres-López C., Pradillo J., Lizasoain I., Moro M.Á

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This mechanism is clinically significant, as tumors with high HIF-1α and PD-L1 expression are often resistant to immunotherapies unless checkpoint inhibitors are used in combination with agents that normalize the TME (160)