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[DOI] [PMC free article] [PubMed] [Google Scholar] Walter P., Ron D

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Together, they underscore the notion that randomized trials and real-world evidence are complementary: RCTs establish efficacy in controlled cohorts, whereas RWE captures performance and applicability in patients who fall outside trial eligibility, enabling a more complete appraisal of safety, effectiveness, and generalizability with a three-dimensional acellular collagen matrix