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Conversely, men have higher risk of inflammation or tissue damage due to higher amount of cytokines and chemokines like IL-2, TNFα, IL-7, IL10, IL-18, CCL14, or CCL23 (144)

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A recent research study showed that in Drosophila exposed to rotenone, lutein-loaded nanoparticles restored DA levels, tyrosine hydroxylase and AChE activity and oxidative stress indicators and improved the survival rate of Drosophila 152 (Table 3) 150 , 152