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Given the cytoprotection concept born in the stomach (innate prevention of the stomach epithelial [16,17] and endothelial [18,19,20,21] cell necrosis that should be extended to other tissue healing), BPC 157, native and stable in human gastric juice can be a cytoprotection mediator as it is not destroyed in human gastric juice for more than 24 h [1,2,3,4,5,6,7,8,9,10,11,27,28,29,30]
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The covalent bond formed between the Halo-tags and the linker is highly specific, irreversible, stable and occurs rapidly under physiological conditions, which facilitates the attachment to a variety of molecules or solid surfaces containing diverse functional groups (Los and Wood, 2006, Los et al., 2008, Ohana et al., 2009)