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The oxidized form is a sulfur-sulfur linked compound known as glutathione disulfide (GSSG)

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Moreover, inhibition of the malate/aspartate shuttle with aminooxyacetic acid (AOA, a potent inhibitor of aspartate aminotransferase) augmented cytosolic NADH/NAD + reflected by elevated lactate/pyruvate and glycerol-3-phosphate/DHAP resulting in a more reductive environment in the cytoplasmic compartment of primary porcine aortic smooth muscle cells (3, 4)