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A notable meta-analysis by Toulis et al

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In conclusion, in the present study, 3-BrPA reduced the HK2 expression and promoted the TXNIP protein expression in TNBC cells by downregulating the expression of c-Myc, thereby inhibiting glycolysis including suppressing lactate generation, intracellular ATP generation and HK activity, inducing mitochondria-regulated apoptosis, and eventually limiting TNBC cell proliferation