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Proceedings of the National Academy of Sciences 2017, 114 (27), 7025–7030

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The authors reported an increased Firmicutes/Bacteroidetes ratio and Streptococcus abundance, with a reduction in Prevotella strains in patients with active MS when compared with healthy controls and patients with MS in remission ( Prevotella strains was inversely associated with Th17 cells in the small intestine, while positively related to disease activity ( 2.4.3 Treatment strategies 2.4.3.1 Probiotics Synergistic therapeutic effects may be exerted by the different strains in probiotic cocktails