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When treated with H 2 O 2 (500 μM, 2 h), GPx1-KD macrophages displayed increased cytotoxicity compared to cells treated with the nsSiRNA (Fig

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In an in vitro cellular assay, aged peripheral blood mononuclear cells treated with quercetin presented a strong proliferative response comparable to that of young cells and increased GSH antioxidant defense levels, significantly reducing the expression of immune senescence markers (166)