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Increased preclinical research also indicates novel ferroptosis-driven therapeutics such as inhibitors of CTNNB1 and GSTA1, SOCE pathways inhibitors, and new nanocarriers such as GOA/miR nanocomplexes and MnO2 nanoflowers that enhance redox balance, recover GPX4 activity, and suppress iron deposition

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Exploration of long-chain vitamin E metabolites for the discovery of a highly potent, orally effective, and metabolically stable 5-LOX inhibitor that limits inflammation

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