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However, prolonged activation can lead to chronic inflammation and a harmful change in function

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In nasopharyngeal cancer, sulforaphane upregulates miR-124-3p, which directly targets STAT3 signaling and reduces cancer stem cell markers, including β-catenin, Nanog, and Oct3/4 in HONE1, SUN1, CNE1, and CNE2 cell lines (125)