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A pilot study administering coenzyme Q 10 (200 mg/day) and vitamin E (2,100 IU/day) to 10 FDRA patients found that energy metabolism of cardiac and skeletal muscle was improved after only three months of therapy (78)

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Unlike gene-edited products where yield penalty can be associated with the disruption of the target genes, the RNAi technology applied to the field may offer more opportunities to manipulate traits of interest in a spatial and temporal context with lesser side effects