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A CRISPR/Cas9-based gene technique carried out on orthotopic tumors in mice resulted in high GSS gene editing efficiency in glioblastoma (up to 67.2%), with negligible off-target gene editing [48]

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[DOI] [PMC free article] [PubMed] [Google Scholar] Polhemus DJ, Calvert JW, Butler J, Lefer DJ (2014)

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