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GSTP1 has the potential for detoxification by conjugating various metabolites of RAN/tobacco with reduced GSH and therefore it is possible that GSTP1 genotypic variations (A313G) with consequential lower enzyme activities, may modify susceptibility to RAN/tobacco metabolites

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In total, 13 genes of the bZIP TF family are upregulated and 19 are downregulated under Cd stress (Yao et al., 2019)