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Alternatively, direct oxidation of amphetamine by DA β-hydroxylase can afford norephedrine

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Four amino-acid substitutions (D-Ala², Gln⁸, Ala¹⁵, Leu²⁷) confer protease resistance and increased potency relative to native GHRH(1-44), but without the DAC linker the plasma half-life remains approximately 30 minutes in published research data