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Cats may be more susceptible than dogs to acetaminophen toxicity since they also lack several UGTs, including UGT1A6 and UGT1A9, which are essential for efficient elimination of acetaminophen by glucuronidation (see further discussion of this below) 28

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Future research must prioritize the transition from foundational discovery to rigorous translational studies, which are essential for bridging the gap between promising preclinical data and tangible clinical applications