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In the process of electron transfer, the complexes interact with each other to form an advanced supramolecular structure known as the supercomplex (SCs) and respiratory corules ( Mitochondrial and Reactive Oxygen Species During ATP generation, ETC, and Krebs cycle inevitably lead to electron leakage, causing incomplete reduction of O 2 and formation of free radicals in a form of superoxide anion (O 2− )

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The active compound is tirzepatide, a synthetic peptide that acts as a dual agonist at both the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R)