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Introductions Traumatic brain injury (TBI) is commonly found following traffic accidents in adults or perinatal asphyxia in newborns, which causes brain swelling with an increase in intracranial pressure and a subsequent decrease in cerebral perfusion leading to ischaemia ( Microtubules stability is a major determinant of axonal growth and neuronal polarization during axon formation (Nogales, 2000)

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it was so wearied as to be taken up by the hand